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TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
In many organisms, the methylation of cytosine in DNA has a key role in silencing ‘parasitic’ DNA elements, regulating transcription and establishing cellular identity. The recent discovery that ten-eleven translocation (TET) proteins are 5-methylcytosine oxidases has provided several chemically pla...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804139/ https://ncbi.nlm.nih.gov/pubmed/23698584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3589 |
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