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Emerging roles of TET proteins and 5-Hydroxymethylcytosines in active DNA demethylation and beyond

Cytosine methylation is the major epigenetic modification of metazoan DNA. Although there is strong evidence that active DNA demethylation occurs in animal cells, the molecular details of this process are unknown. The recent discovery of the TET protein family (TET1–3) 5-methylcytosine hydroxylases...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Junjie U, Su, Yijing, Zhong, Chun, Ming, Guo-li, Song, Hongjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219536/
https://ncbi.nlm.nih.gov/pubmed/21811096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.16.17093
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