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Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain

Mounting evidence points to critical roles for DNA modifications, including 5-methylcytosine (5mC) and its oxidized forms, in the development, plasticity and disorders of the mammalian nervous system. The novel DNA base 5-hydroxymethylcytosine (5hmC) is known to be capable of initiating passive or a...

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Detalhes bibliográficos
Publicado no:Front Biol (Beijing)
Main Authors: GUO, Junjie U., SZULWACH, Keith E., SU, Yijing, LI, Yujing, YAO, Bing, XU, Zihui, SHIN, Joo Heon, XIE, Bing, GAO, Yuan, MING, Guo-li, JIN, Peng, SONG, Hongjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284063/
https://ncbi.nlm.nih.gov/pubmed/25568643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-014-1295-1
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