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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
In contrast to 5-methylcytosine (5-mC), which has been studied extensively(1–3), little is known about 5-hydroxymethylcytosine (5-hmC), a recently identified epigenetic modification present in substantial amounts in certain mammalian cell types(4,5). Here we present a method for determining the geno...
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| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107705/ https://ncbi.nlm.nih.gov/pubmed/21151123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1732 |
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