Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

In contrast to 5-methylcytosine (5-mC), which has been studied extensively(1–3), little is known about 5-hydroxymethylcytosine (5-hmC), a recently identified epigenetic modification present in substantial amounts in certain mammalian cell types(4,5). Here we present a method for determining the geno...

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Bibliografiske detaljer
Main Authors: Song, Chun-Xiao, Szulwach, Keith E, Fu, Ye, Dai, Qing, Yi, Chengqi, Li, Xuekun, Li, Yujing, Chen, Chih-Hsin, Zhang, Wen, Jian, Xing, Wang, Jing, Zhang, Li, Looney, Timothy J, Zhang, Baichen, Godley, Lucy A, Hicks, Leslie M, Lahn, Bruce T, Jin, Peng, He, Chuan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107705/
https://ncbi.nlm.nih.gov/pubmed/21151123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1732
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