Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

DNA methylation plays critical roles in the nervous system and has been traditionally considered to be restricted to CpG dinucleotides in metazoan genomes. Here we show that the single-base resolution DNA methylome from adult mouse dentate neurons consists of both CpG (~75%) and CpH (~25%) methylati...

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Detalhes bibliográficos
Main Authors: Guo, Junjie U., Su, Yijing, Shin, Joo Heon, Shin, Jaehoon, Li, Hongda, Xie, Bin, Zhong, Chun, Hu, Shaohui, Le, Thuc, Fan, Guoping, Zhu, Heng, Chang, Qiang, Gao, Yuan, Ming, Guo-li, Song, Hongjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970219/
https://ncbi.nlm.nih.gov/pubmed/24362762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3607
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