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DNA methylation and hydroxymethylation in hematologic differentiation and transformation
Maintenance of the balance of DNA methylation and demethylation is fundamental for normal cellular development and function. Members of the Ten-Eleven-Translocation (TET) family proteins are Fe(II)- and 2-oxoglutarate-dependent dioxygenases that catalyze sequential oxidation of 5-methylcytosine (5mC...
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| Publicado no: | Curr Opin Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688184/ https://ncbi.nlm.nih.gov/pubmed/26595486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.10.009 |
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