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TET proteins and 5-methylcytosine oxidation in hematological cancers
DNA methylation has pivotal regulatory roles in mammalian development, retrotransposon silencing, genomic imprinting and X-chromosome inactivation. Cancer cells display highly dysregulated DNA methylation profiles characterized by global hypomethylation in conjunction with hypermethylation of promot...
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| Publicado no: | Immunol Rev |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617313/ https://ncbi.nlm.nih.gov/pubmed/25510268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12239 |
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