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TET proteins and 5-methylcytosine oxidation in hematological cancers

DNA methylation has pivotal regulatory roles in mammalian development, retrotransposon silencing, genomic imprinting and X-chromosome inactivation. Cancer cells display highly dysregulated DNA methylation profiles characterized by global hypomethylation in conjunction with hypermethylation of promot...

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Detaylı Bibliyografya
Yayımlandı:Immunol Rev
Asıl Yazarlar: An, Jungeun, Pastor, William A., Ko, Myunggon, Rao, Anjana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617313/
https://ncbi.nlm.nih.gov/pubmed/25510268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12239
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