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TET proteins and the control of cytosine demethylation in cancer
The discovery that ten-eleven translocation (TET) proteins are α-ketoglutarate-dependent dioxygenases involved in the conversion of 5-methylcytosines (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine and 5-carboxycytosine has revealed new pathways in the cytosine methylation and demethylat...
Gespeichert in:
| Veröffentlicht in: | Genome Med |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308928/ https://ncbi.nlm.nih.gov/pubmed/25632305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0134-6 |
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