Gα(s)-Induced Neurodegeneration inCaenorhabditis elegans

Por Berger, Allison J., Hart, Anne C., Kaplan, Joshua M.
Publicado no J Neurosci (1998)

Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications

Por Friend, Samantha F, Deason-Towne, Francina, Peterson, Lisa K, Berger, Allison J, Dragone, Leonard L
Publicado no Am J Clin Exp Immunol (2014)

Insulin-Like Growth Factor-Binding Protein 3 Expression Increases during Immortalization of Cervical Keratinocytes by Human Papillomavirus Type 16 E6 and E7 Proteins

Por Berger, Allison J., Baege, Astrid, Guillemette, Tracy, Deeds, James, Meyer, Ron, Disbrow, Gary, Schlegel, Richard, Schlegel, Robert
Publicado em 2002

Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells

Por Tian, Ze, Zhao, Jian-jun, Tai, Yu-Tzu, Amin, Samir B., Hu, Yiguo, Berger, Allison J., Richardson, Paul, Chauhan, Dharminder, Anderson, Kenneth C.
Publicado em 2012

The Discovery of a Reciprocal Relationship between Tyrosine-Kinase Signaling and Cullin Neddylation

Por Friend, Samantha F., Peterson, Lisa K., Treacy, Eric, Stefanski, Adrianne L., Sosinowski, Tomasz, Pennock, Nathan D., Berger, Allison J., Winn, Virginia D., Dragone, Leonard L.
Publicado em 2013

Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924

Por Jazaeri, Amir A., Shibata, Etsuko, Park, Jonghoon, Bryant, Jennifer L., Conaway, Mark R., Modesitt, Susan C., Smith, Peter G., Milhollen, Michael A., Berger, Allison J., Dutta, Anindya
Publicado em 2013

The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR

Por Zhou, Liang, Chen, Shuang, Zhang, Yu, Kmieciak, Maciej, Leng, Yun, Li, Lihong, Lin, Hui, Rizzo, Kathryn A., Dumur, Catherine I., Ferreira-Gonzalez, Andrea, Rahmani, Mohamed, Povirk, Lawrence, Chalasani, Sri, Berger, Allison J., Dai, Yun, Grant, Steven
Publicado no Blood (2016)

Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies

Por Smith, David C., Kalebic, Thea, Infante, Jeffrey R., Siu, Lillian L., Sullivan, Daniel, Vlahovic, Gordana, Kauh, John S., Gao, Feng, Berger, Allison J., Tirrell, Stephen, Gupta, Neeraj, Di Bacco, Alessandra, Berg, Deborah, Liu, Guohui, Lin, Jianchang, Hui, Ai-Min, Thompson, John A.
Publicado no Invest New Drugs (2015)

KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism

Por Chattopadhyay, Nibedita, Berger, Allison J., Koenig, Erik, Bannerman, Bret, Garnsey, James, Bernard, Hugues, Hales, Paul, Maldonado Lopez, Angel, Yang, Yu, Donelan, Jill, Jordan, Kristen, Tirrell, Stephen, Stringer, Bradley, Xia, Cindy, Hather, Greg, Galvin, Katherine, Manfredi, Mark, Rhodes, Nelson, Amidon, Ben
Publicado no PLoS One (2015)

Phase I Study of the Novel Investigational NEDD8-activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/refractory Multiple Myeloma or Lymphoma

Por Shah, Jatin J., Jakubowiak, Andrzej J., O’Connor, Owen A., Orlowski, Robert Z., Harvey, R. Donald, Smith, Mitchell R., Lebovic, Daniel, Diefenbach, Catherine, Kelly, Kevin, Hua, Zhaowei, Berger, Allison J., Mulligan, George, Faessel, Helene, Tirrell, Stephen, Dezube, Bruce J., Lonial, Sagar
Publicado no Clin Cancer Res (2015)

Antitumor Activity of the Investigational Proteasome Inhibitor MLN9708 in Mouse Models of B-cell and Plasma Cell Malignancies

Por Lee, Edmund C., Fitzgerald, Michael, Bannerman, Bret, Donelan, Jill, Bano, Kristen, Terkelsen, Jennifer, Bradley, Daniel P., Subakan, Ozlem, Silva, Matthew D., Liu, Ray, Pickard, Michael, Li, Zhi, Tayber, Olga, Li, Ping, Hales, Paul, Carsillo, Mary, Neppalli, Vishala T., Berger, Allison J., Kupperman, Erik, Manfredi, Mark, Bolen, Joseph B., Van Ness, Brian, Janz, Siegfried
Publicado em 2011