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Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924
The nearly ubiquitous development of chemoresistant disease remains a major obstacle against improving outcomes for ovarian cancer patients. In this investigation we evaluated the preclinical activity of MLN4924, an investigational inhibitor of the NEDD8-activating enzyme, in ovarian cancer cells. E...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795967/ https://ncbi.nlm.nih.gov/pubmed/23939375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1028 |
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