NEDD8 targeting drug MLN4924 elicits DNA re-replication by stabilizing Cdt1 in S Phase, triggering checkpoint activation, apoptosis and senescence in cancer cells

Por Lin, Jie Jessie, Milhollen, Michael A., Smith, Peter G., Narayanan, Usha, Dutta, Anindya
Publicado em 2010

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy

Por Soucy, Teresa A., Dick, Lawrence R., Smith, Peter G., Milhollen, Michael A., Brownell, James E.
Publicado em 2010

Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-Å resolution

Por Malashkevich, Vladimir N., Schneider, Brian J., McNally, Margaret L., Milhollen, Michael A., Pang, James X., Kim, Peter S.
Publicado em 1999

Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924

Por Jazaeri, Amir A., Shibata, Etsuko, Park, Jonghoon, Bryant, Jennifer L., Conaway, Mark R., Modesitt, Susan C., Smith, Peter G., Milhollen, Michael A., Berger, Allison J., Dutta, Anindya
Publicado em 2013

Mechanistic Studies of Substrate-assisted Inhibition of Ubiquitin-activating Enzyme by Adenosine Sulfamate Analogues

Por Chen, Jesse J., Tsu, Christopher A., Gavin, James M., Milhollen, Michael A., Bruzzese, Frank J., Mallender, William D., Sintchak, Michael D., Bump, Nancy J., Yang, Xiaofeng, Ma, Jingya, Loke, Huay-Keng, Xu, Qing, Li, Ping, Bence, Neil F., Brownell, James E., Dick, Lawrence R.
Publicado em 2011