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The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy

Cancer cells depend on signals that promote cell cycle progression and prevent programmed cell death that would otherwise result from cumulative, aberrant stress. These activities require the temporally controlled destruction of specific intracellular proteins by the ubiquitin-proteasome system (UPS...

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Detalhes bibliográficos
Main Authors: Soucy, Teresa A., Dick, Lawrence R., Smith, Peter G., Milhollen, Michael A., Brownell, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092238/
https://ncbi.nlm.nih.gov/pubmed/21779466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910382898
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