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Inhibition of NEDD8‐conjugation pathway by novel molecules: Potential approaches to anticancer therapy

Cancer cells can survive through the upregulation of cell cycle and the escape from apoptosis induced by numerous cellular stresses. In the normal cells, these biological cascades depend on scheduled proteolytic degradation of regulatory proteins via the ubiquitin–proteasome pathway. Therefore, inte...

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Detalhes bibliográficos
Main Authors: Tanaka, Tomoaki, Nakatani, Tatsuya, Kamitani, Tetsu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826113/
https://ncbi.nlm.nih.gov/pubmed/22306028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.003
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