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Inhibition of NEDD8‐conjugation pathway by novel molecules: Potential approaches to anticancer therapy
Cancer cells can survive through the upregulation of cell cycle and the escape from apoptosis induced by numerous cellular stresses. In the normal cells, these biological cascades depend on scheduled proteolytic degradation of regulatory proteins via the ubiquitin–proteasome pathway. Therefore, inte...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826113/ https://ncbi.nlm.nih.gov/pubmed/22306028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.003 |
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