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Inhibition of NEDD8 and FAT10 ligase activities through the degrading enzyme NEDD8 ultimate buster 1: A potential anticancer approach

The capabilities of tumour cells to survive through deregulated cell cycles and evade apoptosis are hallmarks of cancer. The ubiquitin-like proteins (UBL) proteasome system is important in regulating cell cycles via signaling proteins. Deregulation of the proteasomal system can lead to uncontrolled...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Tan, Ka-Liong, Pezzella, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228310/
https://ncbi.nlm.nih.gov/pubmed/28101194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5232
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