Exposure–safety–efficacy analysis of single-agent ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma: dose selection for a phase 3 maintenance study...

מאת Gupta, Neeraj, Labotka, Richard, Liu, Guohui, Hui, Ai-Min, Venkatakrishnan, Karthik
הוצא לאור ב Invest New Drugs (2016)

Increased DNA Methyltransferase Expression Is Associated with an Early Stage of Human Hepatocarcinogenesis

מאת Sun, Lin, Hui, Ai‐Min, Kanai, Yae, Sakamoto, Michiie, Hirohashi, Setsuo
הוצא לאור ב Jpn J Cancer Res (1997)

Switching from body surface area-based to fixed dosing for the investigational proteasome inhibitor ixazomib: a population pharmacokinetic analysis

מאת Gupta, Neeraj, Zhao, Yuan, Hui, Ai-Min, Esseltine, Dixie-Lee, Venkatakrishnan, Karthik
הוצא לאור ב Br J Clin Pharmacol (2015)

The Effect of a High‐Fat Meal on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor, in Patients With Advanced Solid Tumors or Lymphoma

מאת Gupta, Neeraj, Hanley, Michael J., Venkatakrishnan, Karthik, Wang, Bingxia, Sharma, Sunil, Bessudo, Alberto, Hui, Ai‐Min, Nemunaitis, John
הוצא לאור ב J Clin Pharmacol (2016)

Frequent trefoil factor 3 (TFF3) overexpression and promoter hypomethylation in mouse and human hepatocellular carcinomas

מאת OKADA, HARUHIKO, KIMURA, MAKOTO T., TAN, DONGFENG, FUJIWARA, KYOKO, IGARASHI, JUN, MAKUUCHI, MASATOSHI, HUI, AI-MIN, TSURUMARU, MASAHIKO, NAGASE, HIROKI
יצא לאור 2005

A pharmacokinetics and safety phase 1/1b study of oral ixazomib in patients with multiple myeloma and severe renal impairment or end‐stage renal disease requiring haemodialysis

מאת Gupta, Neeraj, Hanley, Michael J., Harvey, R. Donald, Badros, Ashraf, Lipe, Brea, Kukreti, Vishal, Berdeja, Jesus, Yang, Huyuan, Hui, Ai‐Min, Qian, Mark, Zhang, Xiaoquan, Venkatakrishnan, Karthik, Chari, Ajai
הוצא לאור ב Br J Haematol (2016)

Phase 1 study of weekly dosing with the investigational oral proteasome inhibitor ixazomib in relapsed/refractory multiple myeloma

מאת Kumar, Shaji K., Bensinger, William I., Zimmerman, Todd M., Reeder, Craig B., Berenson, James R., Berg, Deborah, Hui, Ai-Min, Gupta, Neeraj, Di Bacco, Alessandra, Yu, Jiang, Shou, Yaping, Niesvizky, Ruben
הוצא לאור ב Blood (2014)

Phase 1 study of twice-weekly ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma patients

מאת Richardson, Paul G., Baz, Rachid, Wang, Michael, Jakubowiak, Andrzej J., Laubach, Jacob P., Harvey, R. Donald, Talpaz, Moshe, Berg, Deborah, Liu, Guohui, Yu, Jiang, Gupta, Neeraj, Di Bacco, Alessandra, Hui, Ai-Min, Lonial, Sagar
הוצא לאור ב Blood (2014)

Pharmacokinetics and safety of ixazomib plus lenalidomide–dexamethasone in Asian patients with relapsed/refractory myeloma: a phase 1 study

מאת Gupta, Neeraj, Goh, Yeow Tee, Min, Chang-Ki, Lee, Jae Hoon, Kim, Kihyun, Wong, Raymond S. M., Chim, Chor Sang, Hanley, Michael J., Yang, Huyuan, Venkatakrishnan, Karthik, Hui, Ai-Min, Esseltine, Dixie-Lee, Chng, Wee Joo
הוצא לאור ב J Hematol Oncol (2015)

A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis

מאת Sanchorawala, Vaishali, Palladini, Giovanni, Kukreti, Vishal, Zonder, Jeffrey A., Cohen, Adam D., Seldin, David C., Dispenzieri, Angela, Jaccard, Arnaud, Schönland, Stefan O., Berg, Deborah, Yang, Huyuan, Gupta, Neeraj, Hui, Ai-Min, Comenzo, Raymond L., Merlini, Giampaolo
הוצא לאור ב Blood (2017)

Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies

מאת Smith, David C., Kalebic, Thea, Infante, Jeffrey R., Siu, Lillian L., Sullivan, Daniel, Vlahovic, Gordana, Kauh, John S., Gao, Feng, Berger, Allison J., Tirrell, Stephen, Gupta, Neeraj, Di Bacco, Alessandra, Berg, Deborah, Liu, Guohui, Lin, Jianchang, Hui, Ai-Min, Thompson, John A.
הוצא לאור ב Invest New Drugs (2015)