Prediction of Hepatic Efflux Transporter-mediated Drug Interactions: When is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?

Por Guo, Cen, Yang, Kyunghee, Liao, Mingxiang, Xia, Cindy Q., Brouwer, Kenneth R., Brouwer, Kim L.R.
Publicado no J Pharm Sci (2017)

KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism

Por Chattopadhyay, Nibedita, Berger, Allison J., Koenig, Erik, Bannerman, Bret, Garnsey, James, Bernard, Hugues, Hales, Paul, Maldonado Lopez, Angel, Yang, Yu, Donelan, Jill, Jordan, Kristen, Tirrell, Stephen, Stringer, Bradley, Xia, Cindy, Hather, Greg, Galvin, Katherine, Manfredi, Mark, Rhodes, Nelson, Amidon, Ben
Publicado no PLoS One (2015)

Application of Receiver Operating Characteristic Analysis to Refine the Prediction of Potential Digoxin Drug Interactions

Por Ellens, Harma, Deng, Shibing, Coleman, JoAnn, Bentz, Joe, Taub, Mitchell E., Ragueneau-Majlessi, Isabelle, Chung, Sophie P., Herédi-Szabó, Krisztina, Neuhoff, Sibylle, Palm, Johan, Balimane, Praveen, Zhang, Lei, Jamei, Masoud, Hanna, Imad, O’Connor, Michael, Bednarczyk, Dallas, Forsgard, Malin, Chu, Xiaoyan, Funk, Christoph, Guo, Ailan, Hillgren, Kathleen M., Li, LiBin, Pak, Anne Y., Perloff, Elke S., Rajaraman, Ganesh, Salphati, Laurent, Taur, Jan-Shiang, Weitz, Dietmar, Wortelboer, Heleen M., Xia, Cindy Q., Xiao, Guangqing, Yamagata, Tetsuo, Lee, Caroline A.
Publicado em 2013

Variability in P-Glycoprotein Inhibitory Potency (IC(50)) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Deci...

Por Bentz, Joe, O’Connor, Michael P., Bednarczyk, Dallas, Coleman, JoAnn, Lee, Caroline, Palm, Johan, Pak, Y. Anne, Perloff, Elke S., Reyner, Eric, Balimane, Praveen, Brännström, Marie, Chu, Xiaoyan, Funk, Christoph, Guo, Ailan, Hanna, Imad, Herédi-Szabó, Krisztina, Hillgren, Kate, Li, Libin, Hollnack-Pusch, Evelyn, Jamei, Masoud, Lin, Xuena, Mason, Andrew K., Neuhoff, Sibylle, Patel, Aarti, Podila, Lalitha, Plise, Emile, Rajaraman, Ganesh, Salphati, Laurent, Sands, Eric, Taub, Mitchell E., Taur, Jan-Shiang, Weitz, Dietmar, Wortelboer, Heleen M., Xia, Cindy Q., Xiao, Guangqing, Yabut, Jocelyn, Yamagata, Tetsuo, Zhang, Lei, Ellens, Harma
Publicado em 2013