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Gα(s)-Induced Neurodegeneration inCaenorhabditis elegans

We describe a genetic model for neurodegeneration in the nematodeCaenorhabditis elegans. Constitutive activation of the GTP-binding protein Gα(s) induces neurodegeneration. Neuron loss occurs in two phases whereby affected cells undergo a swelling response in young larvae and subsequently die someti...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Berger, Allison J., Hart, Anne C., Kaplan, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792578/
https://ncbi.nlm.nih.gov/pubmed/9526004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-08-02871.1998
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