Brain and Whole-Body Imaging of Nociceptin/Orphanin FQ Peptide Receptor in Humans Using the PET Ligand (11)C-NOP-1A

Por Lohith, Talakad G., Zoghbi, Sami S., Morse, Cheryl L., Araneta, Maria F., Barth, Vanessa N., Goebl, Nancy A., Tauscher, Johannes T., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2012

Retest imaging of [(11)C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in brain of healthy humans

Por Lohith, Talakad G., Zoghbi, Sami S., Morse, Cheryl L., Araneta, Maria D. Ferraris, Barth, Vanessa N., Goebl, Nancy A., Tauscher, Johannes T., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2013

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain

Por Wang, Changning, Eessalu, Thomas E, Barth, Vanessa N, Mitch, Charles H, Wagner, Florence F, Hong, Yijia, Neelamegam, Ramesh, Schroeder, Frederick A, Holson, Edward B, Haggarty, Stephen J, Hooker, Jacob M
Publicado em 2013

(11)C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains

Por Zanotti-Fregonara, Paolo, Barth, Vanessa N, Zoghbi, Sami S, Liow, Jeih-San, Nisenbaum, Eric, Siuda, Edward, Gladding, Robert L, Rallis-Frutos, Denise, Morse, Cheryl, Tauscher, Johannes, Pike, Victor W, Innis, Robert B
Publicado em 2013

An Improved Antagonist Radiotracer for the Kappa Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989

Por Zheng, Ming-Qiang, Kim, Su Jin, Holden, Daniel, Lin, Shu-fei, Need, Anne, Rash, Karen, Barth, Vanessa, Mitch, Charles, Navarro, Antonio, Kapinos, Michael, Maloney, Kathleen, Ropchan, Jim, Carson, Richard E., Huang, Yiyun
Publicado no J Nucl Med (2014)

A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies

Por Post, Anke, Smart, Trevor S, Krikke-Workel, Judith, Dawson, Gerard R, Harmer, Catherine J, Browning, Michael, Jackson, Kimberley, Kakar, Rishi, Mohs, Richard, Statnick, Michael, Wafford, Keith, McCarthy, Andrew, Barth, Vanessa, Witkin, Jeffrey M
Publicado no Neuropsychopharmacology (2016)

A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies

Por Post, Anke, Smart, Trevor S, Krikke-Workel, Judith, Dawson, Gerard R, Harmer, Catherine J, Browning, Michael, Jackson, Kimberley, Kakar, Rishi, Mohs, Richard, Statnick, Michael, Wafford, Keith, McCarthy, Andrew, Barth, Vanessa, Witkin, Jeffrey M
Publicado no Neuropsychopharmacology (2016)

Brain and Whole-Body Imaging in Rhesus Monkeys of (11)C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors

Por Kimura, Yasuyuki, Fujita, Masahiro, Hong, Jinsoo, Lohith, Talakad G., Gladding, Robert L., Zoghbi, Sami S., Tauscher, Johannes A., Goebl, Nancy, Rash, Karen S., Chen, Zhaogen, Pedregal, Concepcion, Barth, Vanessa N., Pike, Victor W., Innis, Robert B.
Publicado em 2011

Synthesis and Evaluation of [(11)C]LY2795050 as a Novel Kappa Opioid Receptor Antagonist Radiotracer for PET Imaging

Por Zheng, Ming-Qiang, Nabulsi, Nabeel, Kim, Su Jin, Tomasi, Giampaolo, Lin, Shu-fei, Mitch, Charles, Quimby, Steven, Barth, Vanessa, Rash, Karen, Masters, John, Navarro, Antonio, Seest, Eric, Morris, Evan E., Carson, Richard E., Huang, Yiyun
Publicado em 2013

Synthesis and Evaluation of Radioligands for Imaging Brain Nociceptin/Orphanin FQ Peptide (NOP) Receptors with Positron Emission Tomography

Por Pike, Victor W., Rash, Karen S., Chen, Zhaogen, Pedregal, Concepción, Statnick, Michael A., Kimura, Yasuyuki, Hong, Jinsoo, Zoghbi, Sami S., Fujita, Masahiro, Toledo, Miguel A., Diaz, Nuria, Gackenheimer, Susan L., Tauscher, Johannes T., Barth, Vanessa N., Innis, Robert B.
Publicado em 2011

Pseudoreference Regions for Glial Imaging with (11)C-PBR28: Investigation in 2 Clinical Cohorts

Por Albrecht, Daniel S., Normandin, Marc D., Shcherbinin, Sergey, Wooten, Dustin W., Schwarz, Adam J., Zürcher, Nicole R., Barth, Vanessa N., Guehl, Nicolas J., Akeju, Oluwaseun, Atassi, Nazem, Veronese, Mattia, Turkheimer, Federico, Hooker, Jacob M., Loggia, Marco L.
Publicado no J Nucl Med (2018)

Evaluation in vitro and in animals of a new (11)C-labeled PET radioligand for metabotropic glutamate receptors 1 in brain

Por Zanotti-Fregonara, Paolo, Barth, Vanessa N., Liow, Jeih-San, Zoghbi, Sami S., Clark, David T., Rhoads, Emily, Siuda, Edward, Heinz, Beverly A., Nisenbaum, Eric, Dressman, Bruce, Joshi, Elizabeth, Luffer-Atlas, Debra, Fisher, Matthew J., Masters, John J., Goebl, Nancy, Kuklish, Steven L., Morse, Cheryl, Tauscher, Johannes, Pike, Victor W., Innis, Robert B.
Publicado em 2012

Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors

Por Witkin, Jeffrey M., Rorick‐Kehn, Linda M., Benvenga, Mark J., Adams, Benjamin L., Gleason, Scott D., Knitowski, Karen M., Li, Xia, Chaney, Steven, Falcone, Julie F., Smith, Janice W., Foss, Julie, Lloyd, Kirsti, Catlow, John T., McKinzie, David L., Svensson, Kjell A., Barth, Vanessa N., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Alfonso, Pedregal, Conception, Martínez‐Grau, Maria A., Post, Anke, Ansonoff, Michael A., Pintar, John E., Statnick, Michael A.
Publicado no Pharmacol Res Perspect (2016)