Synthesis and Evaluation of [(11)C]LY2795050 as a Novel Kappa Opioid Receptor Antagonist Radiotracer for PET Imaging

Kappa opioid receptors (KOR) are believed to be involved in the pathophysiology of depression, anxiety disorders, drug abuse and alcoholism. To date, only one tracer, the kappa opioid receptor agonist [(11)C]GR103545, has been reported to be able to image KOR in primates. The goal of the present stu...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zheng, Ming-Qiang, Nabulsi, Nabeel, Kim, Su Jin, Tomasi, Giampaolo, Lin, Shu-fei, Mitch, Charles, Quimby, Steven, Barth, Vanessa, Rash, Karen, Masters, John, Navarro, Antonio, Seest, Eric, Morris, Evan E., Carson, Richard E., Huang, Yiyun
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775344/
https://ncbi.nlm.nih.gov/pubmed/23353688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.109512
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