Kinetic modeling of (11)C-LY2795050, a novel antagonist radiotracer for PET imaging of the kappa opioid receptor in humans

(11)C-LY2795050 is a novel kappa opioid receptor (KOR) antagonist tracer for positron emission tomography (PET) imaging. The purpose of this first-in-human study was to determine the optimal kinetic model for analysis of (11)C-LY2795050 imaging data. Sixteen subjects underwent baseline scans and blo...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Naganawa, Mika, Zheng, Ming-Qiang, Nabulsi, Nabeel, Tomasi, Giampaolo, Henry, Shannan, Lin, Shu-Fei, Ropchan, Jim, Labaree, David, Tauscher, Johannes, Neumeister, Alexander, Carson, Richard E, Huang, Yiyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269759/
https://ncbi.nlm.nih.gov/pubmed/25182664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.150
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