Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators

Por Lo, Hui-Wen, Cao, Xinyu, Zhu, Hu, Ali-Osman, Francis
Publicado em 2008

COX-2 is a Novel Transcriptional Target of the Nuclear EGFR-STAT3 and EGFRvIII-STAT3 Signaling Axes

Por Lo, Hui-Wen, Cao, Xinyu, Zhu, Hu, Ali-Osman, Francis
Publicado em 2010

EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: A potential mechanism of EGFR-driven antagonism of apoptosis

Por Cao, Xinyu, Zhu, Hu, Ali-Osman, Francis, Lo, Hui-Wen
Publicado em 2011

A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion

Por Lo, Hui-Wen, Zhu, Hu, Cao, Xinyu, Aldrich, Amy, Ali-Osman, Francis
Publicado em 2009

EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity

Por Zhu, Hu, Cao, Xinyu, Ali-Osman, Francis, Keir, Stephen, Lo, Hui-Wen
Publicado em 2010

Disulfiram is a direct and potent inhibitor of human O(6)-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA...

Por Paranjpe, Ameya, Zhang, Ruiwen, Ali-Osman, Francis, Bobustuc, George C., Srivenugopal, Kalkunte S.
Publicado em 2014

Identification and Functional Characterization of the Human Glutathione S-Transferase P1 Gene as a Novel Transcriptional Target of the p53 Tumor Suppressor Gene

Por Lo, Hui-Wen, Stephenson, Lisa, Cao, Xinyu, Milas, Mira, Pollock, Raphael, Ali-Osman, Francis
Publicado em 2008

Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppres...

Por Okamura, Tatsunori, Antoun, Gamil, Keir, Stephen T., Friedman, Henry, Bigner, Darell D., Ali-Osman, Francis
Publicado no J Biol Chem (2015)

Tyrosine Phosphorylation of the Human Glutathione S-Transferase P1 by Epidermal Growth Factor Receptor

Por Okamura, Tatsunori, Singh, Simendra, Buolamwini, John, Haystead, Timothy, Friedman, Henry, Bigner, Darell, Ali-Osman, Francis
Publicado em 2009

Decoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells()

Por Cui, Bo, Johnson, Stewart P., Bullock, Nancy, Ali-Osman, Francis, Bigner, Darell D., Friedman, Henry S.
Publicado em 2010

Mitogen-activated Protein Kinase (MAPK) Hyperactivation and Enhanced NRAS Expression Drive Acquired Vemurafenib Resistance in V600E BRAF Melanoma Cells

Por Lidsky, Michael, Antoun, Gamil, Speicher, Paul, Adams, Bartley, Turley, Ryan, Augustine, Christi, Tyler, Douglas, Ali-Osman, Francis
Publicado em 2014

Endothelial Colony Forming Cells (ECFCs) As a Model for Studying Effects of Low-Dose Ionizing Radiation: Growth Inhibition by a Single Dose

Por Kinev, Alexander V., Levering, Vrad, Young, Kenneth, Ali-Osman, Francis, Truskey, George A., Dewhirst, Mark W., Il’yasova, Dora
Publicado em 2013

Assessment of type of allergy and antihistamine use in the development of glioma

Por McCarthy, Bridget J., Rankin, Kristin, Il'yasova, Dora, Erdal, Serap, Vick, Nicholas, Ali-Osman, Francis, Bigner, Darell D., Davis, Faith
Publicado em 2011

Small ubiquitin‐like modifier 1–3 is activated in human astrocytic brain tumors and is required for glioblastoma cell survival

Por Yang, Wei, Wang, Liangli, Roehn, Gabriele, Pearlstein, Robert D., Ali‐Osman, Francis, Pan, Hongjie, Goldbrunner, Roland, Krantz, Matthew, Harms, Christoph, Paschen, Wulf
Publicado em 2012

Association between glioma and history of allergies, asthma, and eczema: a case-control study with three groups of controls

Por Il’yasova, Dora, McCarthy, Bridget, Marcello, Jennifer, Schildkraut, Joellen M., Moorman, Patricia G., Krishnamachari, Bhuma, Ali-Osman, Francis, Bigner, Darell D., Davis, Faith
Publicado em 2009

Association between body mass index and mortality in patients with glioblastoma mutliforme

Por Jones, Lee W., Ali-Osman, Francis, Lipp, Eric, Marcello, Jennifer E., McCarthy, Bridget, McCoy, Lucie, Rice, Terri, Wrensch, Margaret, Il'yasova, Dora
Publicado em 2010

New insights into estrogenic regulation of O(6)-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or...

Por Paranjpe, Ameya, Bailey, Nathan I., Konduri, Santhi, Bobustuc, George C., Ali-Osman, Francis, Yusuf, Mohd. A., Punganuru, Surendra R., Madala, Hanumantha Rao, Basak, Debasish, Mostofa, AGM, Srivenugopal, Kalkunte S.
Publicado no J Biomed Res (2016)

Mismatch Repair Deficiency Does Not Mediate Clinical Resistance to Temozolomide in Malignant Glioma

Por Maxwell, Jill A., Johnson, Stewart P., McLendon, Roger E., Lister, David W., Horne, Krystle S., Rasheed, Ahmed, Quinn, Jennifer A., Ali-Osman, Francis, Friedman, Allan H., Modrich, Paul L., Bigner, Darell D., Friedman, Henry S.
Publicado em 2008

Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: Implications for drug development

Por Brown, Kristine E., Chagoya, Gustavo, Kwatra, Shawn G., Yen, Timothy, Keir, Stephen T., Cooter, Mary, Hoadley, Katherine A., Rasheed, Ahmed, Lipp, Eric S., Mclendon, Roger, Ali-Osman, Francis, Bigner, Darell D., Sampson, John H., Kwatra, Madan M.
Publicado no J Neurochem (2015)

EPID-01 CHICKEN POX AND GLIOMA RISK: PRELIMINARY RESULTS FROM THE GLIOGENE INTERNATIONAL CASE-CONTROL STUDY

Por Amirian, E. Susan, Scheurer, Michael, Armstrong, Georgina, Zhou, Renke, Lau, Ching, Claus, Elizabeth, Barnholtz-Sloan, Jill, Il'yasova, Dora, Schildkraut, Joellen, Ali-Osman, Francis, Sadetzki, Siegal, Johansen, Christoffer, Houlston, Richard, Jenkins, Robert, Lachance, Daniel, Olson, Sara, Bernstein, Jonine, Merrell, Ryan, Wrensch, Margaret, Davis, Faith, Lai, Rose, Shete, Sanjay, Amos, Christopher I., Melin, Beatrice S., Bondy, Melissa
Publicado no Neuro Oncol (2015)