Decoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells()

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor in adults. Current therapy includes surgery, radiation and chemotherapy with temozolomide (TMZ). Major determinants of clinical response to TMZ include methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) pro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cui, Bo, Johnson, Stewart P., Bullock, Nancy, Ali-Osman, Francis, Bigner, Darell D., Friedman, Henry S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Editorial Department of Journal of Biomedical Research 2010
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596690/
https://ncbi.nlm.nih.gov/pubmed/23554659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(10)60057-7
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