Voltage-dependent processes in the electroneutral amino acid exchanger ASCT2

по Zander, Catherine B., Albers, Thomas, Grewer, Christof
Опубликовано 2013

Defining Substrate and Blocker Activity of Alanine-Serine-Cysteine Transporter 2 (ASCT2) Ligands with Novel Serine Analogs

по Albers, Thomas, Marsiglia, William, Thomas, Taniya, Gameiro, Armanda, Grewer, Christof
Опубликовано 2012

A Conserved Na(+) Binding Site of the Sodium-coupled Neutral Amino Acid Transporter 2 (SNAT2)

по Zhang, Zhou, Albers, Thomas, Fiumera, Heather L., Gameiro, Armanda, Grewer, Christof
Опубликовано 2009

Charge Compensation Mechanism of a Na(+)-coupled, Secondary Active Glutamate Transporter

по Grewer, Christof, Zhang, Zhou, Mwaura, Juddy, Albers, Thomas, Schwartz, Alexander, Gameiro, Armanda
Опубликовано 2012

Protonation State of a Conserved Acidic Amino Acid Involved in Na(+) Binding to the Glutamate Transporter EAAC1

по Mwaura, Juddy, Tao, Zhen, James, Herbert, Albers, Thomas, Schwartz, Alexander, Grewer, Christof
Опубликовано 2012

Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo

по Booth, Laurence, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Poklepovic, Andrew, Lebedyeva, Iryna O., Dent, Paul
Опубликовано в: Oncotarget (2016)

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth

по Lu, Chunwan, Klement, John D., Yang, Dafeng, Albers, Thomas, Lebedyeva, Iryna O., Waller, Jennifer L., Liu, Kebin
Опубликовано в: Cancer Lett (2020)

Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

по Colas, Claire, Grewer, Christof, Otte, Nicholas James, Gameiro, Armanda, Albers, Thomas, Singh, Kurnvir, Shere, Helen, Bonomi, Massimiliano, Holst, Jeff, Schlessinger, Avner
Опубликовано в: PLoS Comput Biol (2015)

Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes

по Coe, Genevieve L., Redd, Priscilla S., Paschall, Amy V., Lu, Chunwan, Gu, Lilly, Cai, Houjian, Albers, Thomas, Lebedyeva, Iryna O., Liu, Kebin
Опубликовано в: Sci Rep (2016)

WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

по Lu, Chunwan, Liu, Zhuoqi, Klement, John D, Yang, Dafeng, Merting, Alyssa D, Poschel, Dakota, Albers, Thomas, Waller, Jennifer L, Shi, Huidong, Liu, Kebin
Опубликовано в: J Immunother Cancer (2021)

Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression

по Li, Qianjin, Alsaidan, Omar Awad, Ma, Yongjie, Kim, Sungjin, Liu, Junchen, Albers, Thomas, Liu, Kebin, Beharry, Zanna, Zhao, Shaying, Wang, Fen, Lebedyeva, Iryna, Cai, Houjian
Опубликовано в: J Biol Chem (2018)

Multi-kinase inhibitors can associate with heat shock proteins through their NH(2)-termini by which they suppress chaperone function

по Booth, Laurence, Shuch, Brian, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Proniuk, Stefan, Zukiwski, Alexander, Wang, Dasheng, Chen, Ching-Shih, Bottaro, Don, Ecroyd, Heath, Lebedyeva, Iryna O., Dent, Paul
Опубликовано в: Oncotarget (2016)

Blocking myristoylation of Src inhibits its kinase activity and suppresses prostate cancer progression

по Kim, Sungjin, Alsaidan, Omar Awad, Goodwin, Octavia, Li, Qianjin, Sulejmani, Essilvo, Han, Zhen, Bai, Aiping, Albers, Thomas, Beharry, Zanna, Zheng, Y. George, Norris, James S., Szulc, Zdzislaw M., Bielawska, Alicja, Lebedyeva, Iryna, Pegan, Scott D., Cai, Houjian
Опубликовано в: Cancer Res (2017)

SUV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion

по Lu, Chunwan, Yang, Dafeng, Klement, John D., Oh, Kyu, Savage, Natasha M., Waller, Jennifer L., Colby, Aaron H., Grinstaff, Mark W., Oberlies, Nicholas H., Pearce, Cedric J., Xie, Zhiliang, Kulp, Samuel K., Coss, Christopher C., Phelps, Mitch A., Albers, Thomas, Lebedyeva, Iryna O., Liu, Kebin
Опубликовано в: Cancer Immunol Res (2019)