Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer

Por Poklepovic, Andrew, Gewirtz, David A
Publicado em 2014

PDE5 inhibitors enhance the lethality of [pemetrexed + sorafenib]

Por Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Dent, Paul
Publicado no Oncotarget (2017)

Pazopanib and HDAC inhibitors interact to kill sarcoma cells

Por Tavallai, Seyedmehrad, Hamed, Hossein A, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Publicado em 2014

Sorafenib/Regorafenib and Lapatinib interact to kill CNS tumor cells

Por Hamed, Hossein A., Tavallai, Seyedmehrad, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Publicado em 2015

Rationally Repurposing Ruxolitinib (Jakafi(®)) as a Solid Tumor Therapeutic

Por Tavallai, Mehrad, Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Dent, Paul
Publicado no Front Oncol (2016)

PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide

Por Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Gordon, Sarah, Dent, Paul
Publicado no Oncotarget (2016)

Poly(ADP-ribose) Polymerase 1 Modulates the Lethality of CHK1 Inhibitors in Mammary Tumors

Por Tang, Yong, Hamed, Hossein A., Poklepovic, Andrew, Dai, Yun, Grant, Steven, Dent, Paul
Publicado em 2012

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress inducing drugs

Por Booth, Laurence, Roberts, Jane L., Cruickshanks, Nichola, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Publicado em 2014

Regulation of dimethyl-fumarate toxicity by proteasome inhibitors

Por Booth, Laurence, Cruickshanks, Nichola, Tavallai, Seyedmehrad, Roberts, Jane L, Peery, Matthew, Poklepovic, Andrew, Dent, Paul
Publicado no Cancer Biol Ther (2014)

Ruxolitinib synergizes with DMF to kill via BIM+BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROS

Por Tavallai, Mehrad, Booth, Laurence, Roberts, Jane L., McGuire, William P., Poklepovic, Andrew, Dent, Paul
Publicado no Oncotarget (2016)

Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells

Por Tang, Yong, Yacoub, Adly, Hamed, Hossein A., Poklepovic, Andrew, Tye, Gary W., Grant, Steven, Dent, Paul
Publicado em 2012

Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo

Por Booth, Laurence, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Poklepovic, Andrew, Lebedyeva, Iryna O., Dent, Paul
Publicado no Oncotarget (2016)

The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo

Por Booth, Laurence, Roberts, Jane L., Sander, Cindy, Lee, John, Kirkwood, John M., Poklepovic, Andrew, Dent, Paul
Publicado no Oncotarget (2017)

Lapatinib and Obatoclax Kill Tumor Cells through Blockade of ERBB1/3/4 and through Inhibition of BCL-xL and MCL-1

Por Cruickshanks, Nichola, Hamed, Hossein A., Bareford, M. Danielle, Poklepovic, Andrew, Fisher, Paul B., Grant, Steven, Dent, Paul
Publicado em 2012

HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells

Por Booth, Laurence, Roberts, Jane L, Conley, Adam, Cruickshanks, Nichola, Ridder, Thomas, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Publicado em 2014

Automated determination of metastases in unstructured radiology reports for eligibility screening in oncology clinical trials

Por Petkov, Valentina I., Penberthy, Lynne T., Dahman, Bassam A., Poklepovic, Andrew, Gillam, Chris W., McDermott, James H.
Publicado no Exp Biol Med (Maywood) (2013)

OSU‐03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood–Brain Barrier: Implications for Anti‐Cancer Therapies

Por Booth, Laurence, Roberts, Jane L., Tavallai, Mehrad, Nourbakhsh, Aida, Chuckalovcak, John, Carter, Jori, Poklepovic, Andrew, Dent, Paul
Publicado no J Cell Physiol (2015)

Celecoxib enhances [sorafenib + sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistance

Por Webb, Timothy, Carter, Jori, Roberts, Jane L, Poklepovic, Andrew, McGuire, William P, Booth, Laurence, Dent, Paul
Publicado no Cancer Biol Ther (2015)

Differential regulation of autophagy and cell viability by ceramide species

Por Cruickshanks, Nichola, Roberts, Jane L, Bareford, M Danielle, Tavallai, Mehrad, Poklepovic, Andrew, Booth, Laurence, Spiegel, Sarah, Dent, Paul
Publicado no Cancer Biol Ther (2015)

Nexavar/Stivarga and Viagra Interact to Kill Tumor Cells

Por Tavallai, Mehrad, Hamed, Hossein A., Roberts, Jane L., Cruickshanks, Nichola, Chuckalovcak, John, Poklepovic, Andrew, Booth, Laurence, Dent, Paul
Publicado no J Cell Physiol (2015)