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Nexavar/Stivarga and Viagra Interact to Kill Tumor Cells
We determined whether the multi‐kinase inhibitor sorafenib or its derivative regorafenib interacted with phosphodiesterase 5 (PDE5) inhibitors such as Viagra (sildenafil) to kill tumor cells. PDE5 and PDGFRα/β were over‐expressed in liver tumors compared to normal liver tissue. In multiple cell type...
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| Publicado no: | J Cell Physiol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835179/ https://ncbi.nlm.nih.gov/pubmed/25704960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24961 |
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