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Sorafenib/Regorafenib and Lapatinib interact to kill CNS tumor cells

The present studies were to determine whether the multi-kinase inhibitor sorafenib or its derivative regorafenib interacted with the ERBB1/ERBB2 inhibitor lapatinib to kill CNS tumor cells. In multiple CNS tumor cell types sorafenib and lapatinib interacted in a greater than additive fashion to caus...

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Detalhes bibliográficos
Main Authors: Hamed, Hossein A., Tavallai, Seyedmehrad, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182138/
https://ncbi.nlm.nih.gov/pubmed/24911215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24689
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