Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells

The present studies were designed to determine whether the multi-kinase inhibitor sorafenib (Nexavar) interacted with histone deacetylase inhibitors to kill glioblastoma and medulloblastoma cells. In a dose-dependent fashion sorafenib lethality was enhanced in multiple genetically disparate primary...

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Bibliografiske detaljer
Main Authors: Tang, Yong, Yacoub, Adly, Hamed, Hossein A., Poklepovic, Andrew, Tye, Gary W., Grant, Steven, Dent, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679096/
https://ncbi.nlm.nih.gov/pubmed/22406992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.19771
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