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Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells
The present studies were designed to determine whether the multi-kinase inhibitor sorafenib (Nexavar) interacted with histone deacetylase inhibitors to kill glioblastoma and medulloblastoma cells. In a dose-dependent fashion sorafenib lethality was enhanced in multiple genetically disparate primary...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679096/ https://ncbi.nlm.nih.gov/pubmed/22406992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.19771 |
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