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Pazopanib and HDAC inhibitors interact to kill sarcoma cells
The present studies were to determine whether the multi-kinase inhibitor pazopanib interacted with histone deacetylase inhibitors (HDACI: valproate, vorinostat) to kill sarcoma cells. In multiple sarcoma cell lines, at clinically achievable doses, pazopanib and HDACI interacted in an additive to gre...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026080/ https://ncbi.nlm.nih.gov/pubmed/24556916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28163 |
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