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The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib

Sarcomas are a diverse set of malignancies. For soft tissue sarcomas, the kinase and chaperone inhibitor pazopanib is a standard of care therapeutic. Previously, we demonstrated that HDAC inhibitors enhanced pazopanib lethality against sarcoma and other tumor cell types in vitro and in vivo. The pre...

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發表在:Front Oncol
Main Authors: Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Dent, Paul
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657367/
https://ncbi.nlm.nih.gov/pubmed/31380285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00650
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