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Palbociclib augments Neratinib killing of tumor cells that is further enhanced by HDAC inhibition
Cancers expressing mutant RAS are associated with a weaker response to chemotherapy and a shorter overall patient survival. We have demonstrated that the irreversible inhibitor of ERBB1/2/4, neratinib, inhibits ERBB1/2/4 and causes their internalization and autolysosomal degradation. Fellow-traveler...
Shranjeno v:
| izdano v: | Cancer Biol Ther |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6343717/ https://ncbi.nlm.nih.gov/pubmed/30183517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1507665 |
| Oznake: |
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