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Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer
The premise of inhibiting autophagy to overcome resistance to chemotherapy has been investigated in 5 clinical phase I trials combining hydroxychloroquine with vorinostat, temsirolimus, temozolomide, or bortezomib. These studies have provided a number of insights relating to the tolerability of the...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Landes Bioscience
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203528/ https://ncbi.nlm.nih.gov/pubmed/24991829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29428 |
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