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HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells
The present studies determined whether the antibiotic salinomycin interacted with HDAC inhibitors to kill primary human GBM cells. Regardless of PTEN, ERBB1, or p53 mutational status salinomycin interacted with HDAC inhibitors in a synergistic fashion to kill GBM cells. Inhibition of CD95/Caspase 8...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974832/ https://ncbi.nlm.nih.gov/pubmed/24351423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27309 |
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