Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Dent, Paul, Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Hancock, John F.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997152/
https://ncbi.nlm.nih.gov/pubmed/32047722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00022
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