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Fingolimod Augments Monomethylfumarate Killing of GBM Cells
Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...
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| Izdano u: | Front Oncol |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6997152/ https://ncbi.nlm.nih.gov/pubmed/32047722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00022 |
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