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Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...

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Podrobná bibliografie
Vydáno v:Front Oncol
Hlavní autoři: Dent, Paul, Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Hancock, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997152/
https://ncbi.nlm.nih.gov/pubmed/32047722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00022
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