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Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Dent, Paul, Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Hancock, John F.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997152/
https://ncbi.nlm.nih.gov/pubmed/32047722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00022
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