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Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Dent, Paul, Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Hancock, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997152/
https://ncbi.nlm.nih.gov/pubmed/32047722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00022
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