HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells

The present studies determined whether the antibiotic salinomycin interacted with HDAC inhibitors to kill primary human GBM cells. Regardless of PTEN, ERBB1, or p53 mutational status salinomycin interacted with HDAC inhibitors in a synergistic fashion to kill GBM cells. Inhibition of CD95/Caspase 8...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Booth, Laurence, Roberts, Jane L, Conley, Adam, Cruickshanks, Nichola, Ridder, Thomas, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974832/
https://ncbi.nlm.nih.gov/pubmed/24351423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27309
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