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PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells
We determined whether clinically relevant phosphodiesterase 5 (PDE5) inhibitors interacted with clinically relevant chemotherapies to kill medulloblastoma cells. In medulloblastoma cells PDE5 inhibitors interacted in a greater than additive fashion with vincristine/etoposide/cisplatin to cause cell...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049791/ https://ncbi.nlm.nih.gov/pubmed/24651037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28553 |
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