PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells

We determined whether clinically relevant phosphodiesterase 5 (PDE5) inhibitors interacted with clinically relevant chemotherapies to kill medulloblastoma cells. In medulloblastoma cells PDE5 inhibitors interacted in a greater than additive fashion with vincristine/etoposide/cisplatin to cause cell...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Roberts, Jane L, Booth, Laurence, Conley, Adam, Cruickshanks, Nichola, Malkin, Mark, Kukreja, Rakesh C, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049791/
https://ncbi.nlm.nih.gov/pubmed/24651037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28553
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki