Computational Design of Membrane Proteins

Por Perez-Aguilar, Jose Manuel, Saven, Jeffery G.
Publicado em 2012

Human μ Opioid Receptor Models with Evaluation of the Accuracy Using the Crystal Structure of the Murine μ Opioid Receptor

Por Perez-Aguilar, Jose Manuel, Saven, Jeffery G., Liu, Renyu
Publicado em 2012

Binding Site and Affinity Prediction of General Anesthetics to Protein Targets Using Docking

Por Liu, Renyu, Perez-Aguilar, Jose Manuel, Liang, David, Saven, Jeffery G.
Publicado em 2012

An In Silico study of TiO(2) nanoparticles interaction with twenty standard amino acids in aqueous solution

Por Liu, Shengtang, Meng, Xuan-Yu, Perez-Aguilar, Jose Manuel, Zhou, Ruhong
Publicado no Sci Rep (2016)

A Functional Selectivity Mechanism at the Serotonin-2A GPCR Involves Ligand-Dependent Conformations of Intracellular Loop 2

Por Perez-Aguilar, Jose Manuel, Shan, Jufang, LeVine, Michael V., Khelashvili, George, Weinstein, Harel
Publicado no J Am Chem Soc (2014)

Molecular recognition of ketamine by a subset of olfactory G protein–coupled receptors

Por Ho, Jianghai, Perez-Aguilar, Jose Manuel, Gao, Lu, Saven, Jeffery G., Matsunami, Hiroaki, Eckenhoff, Roderic G.
Publicado no Sci Signal (2015)

Phosphorylation Regulates the Secondary Structure and Function of Dentin Phosphoprotein Peptides

Por Villarreal-Ramirez, Eduardo, Eliezer, David, Garduño-Juarez, Ramon, Gericke, Arne, Perez-Aguilar, Jose Manuel, Boskey, Adele
Publicado no Bone (2016)

A Computationally Designed Water-Soluble Variant of a G-Protein-Coupled Receptor: The Human Mu Opioid Receptor

Por Perez-Aguilar, Jose Manuel, Xi, Jin, Matsunaga, Felipe, Cui, Xu, Selling, Bernard, Saven, Jeffery G., Liu, Renyu
Publicado em 2013

HIV Diagnosis, Linkage to Care, and Retention among Men Who Have Sex with Men and Transgender Women in Guatemala City

Por Barrington, Clare, Knudston, Kelly, Bailey, Olga Alicia Paz, Aguilar, Jose Manuel, Loya-Montiel, Marilu Itzel, Morales-Miranda, Sonia
Publicado no J Health Care Poor Underserved (2016)

Characterization of a Computationally Designed Water-soluble Human μ Opioid Receptor Variant Using X-ray Structural Information

Por Zhao, Xuelian, Perez-Aguilar, Jose Manuel, atsunaga, Felipe, Lerner, Mitchell, Xi, Jin, Selling, Bernard, Johnson, A. T. Charlie, Saven, Jeffery G., Liu, Renyu
Publicado em 2014

Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2–ADAM17-dependent proteolysis

Por Li, Xue, Maretzky, Thorsten, Perez-Aguilar, Jose Manuel, Monette, Sébastien, Weskamp, Gisela, Le Gall, Sylvain, Beutler, Bruce, Weinstein, Harel, Blobel, Carl P.
Publicado no J Cell Sci (2017)

Differential Pd-nanocrystal facets demonstrate distinct antibacterial activity against Gram-positive and Gram-negative bacteria

Por Fang, Ge, Li, Weifeng, Shen, Xiaomei, Perez-Aguilar, Jose Manuel, Chong, Yu, Gao, Xingfa, Chai, Zhifang, Chen, Chunying, Ge, Cuicui, Zhou, Ruhong
Publicado no Nat Commun (2018)

Multiple Hindered Rotators in a Gyroscope-Inspired Tribenzylamine Hemicryptophane

Por Khan, Najat S., Perez-Aguilar, Jose Manuel, Kaufmann, Tara, Hill, P. Aru, Taratula, Olena, Lee, One-Sun, Carroll, Patrick J., Saven, Jeffery G., Dmochowski, Ivan J.
Publicado em 2011

Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein

Por Polizzi, Nicholas F., Eibling, Matthew J., Perez-Aguilar, Jose Manuel, Rawson, Jeff, Lanci, Christopher J., Fry, H. Christopher, Beratan, David N., Saven, Jeffery G., Therien, Michael J.
Publicado no J Am Chem Soc (2016)

NMR Structure and Dynamics of a Designed Water-soluble Transmembrane Domain of Nicotinic Acetylcholine Receptor

Por Cui, Tanxing, Mowrey, David, Bondarenko, Vasyl, Tillman, Tommy, Ma, Dejian, Landrum, Elizabeth, Perez-Aguilar, Jose Manuel, He, Jing, Wang, Wei, Saven, Jeffery G., Eckenhoff, Roderic G., Tang, Pei, Xu, Yan
Publicado em 2011

Scalable Production of Highly Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor

Por Lerner, Mitchell B., Matsunaga, Felipe, Han, Gang Hee, Hong, Sung Ju, Xi, Jin, Crook, Alexander, Perez-Aguilar, Jose Manuel, Park, Yung Woo, Saven, Jeffery G., Liu, Renyu, Johnson, A. T. Charlie
Publicado em 2014

Single-molecule analysis of ligand efficacy in β(2)AR-G protein activation

Por Gregorio, G. Glenn, Masureel, Matthieu, Hilger, Daniel, Terry, Daniel S., Juette, Manuel, Zhao, Hong, Zhou, Zhou, Perez-Aguilar, Jose Manuel, Hauge, Maria, Mathiasen, Signe, Javitch, Jonathan A., Weinstein, Harel, Kobilka, Brian K., Blanchard, Scott C.
Publicado no Nature (2017)

Computational Protein Design to Re-Engineer Stromal Cell-Derived Factor-1α (SDF) Generates an Effective and Translatable Angiogenic Polypeptide Analog

Por Hiesinger, William, Perez-Aguilar, Jose Manuel, Atluri, Pavan, Marotta, Nicole A., Frederick, John R., Fitzpatrick, J. Raymond, McCormick, Ryan C., Muenzer, Jeffrey R., Yang, Elaine C., Levit, Rebecca D., Yuan, Li-Jun, MacArthur, John W., Saven, Jeffery G., Woo, Y. Joseph
Publicado em 2011