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NMR Structure and Dynamics of a Designed Water-soluble Transmembrane Domain of Nicotinic Acetylcholine Receptor
The nicotinic acetylcholine receptor (nAChR) is an important therapeutic target for a wide range of pathophysiological conditions, for which rational drug designs often require receptor structures at atomic resolution. Recent proof-of-concept studies demonstrated a water-solubilization approach to s...
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| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273582/ https://ncbi.nlm.nih.gov/pubmed/22155685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.11.021 |
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