NMR Structure and Dynamics of a Designed Water-soluble Transmembrane Domain of Nicotinic Acetylcholine Receptor

The nicotinic acetylcholine receptor (nAChR) is an important therapeutic target for a wide range of pathophysiological conditions, for which rational drug designs often require receptor structures at atomic resolution. Recent proof-of-concept studies demonstrated a water-solubilization approach to s...

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Détails bibliographiques
Auteurs principaux: Cui, Tanxing, Mowrey, David, Bondarenko, Vasyl, Tillman, Tommy, Ma, Dejian, Landrum, Elizabeth, Perez-Aguilar, Jose Manuel, He, Jing, Wang, Wei, Saven, Jeffery G., Eckenhoff, Roderic G., Tang, Pei, Xu, Yan
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273582/
https://ncbi.nlm.nih.gov/pubmed/22155685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.11.021
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