Wird geladen...

Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain

An extensive search for isoflurane binding sites in the nicotinic acetylcholine receptor (nAChR) and the proton gated ion channel from Gloebacter violaceus (GLIC) has been carried out based on molecular dynamics (MD) simulations in fully hydrated lipid membrane environments. Isoflurane introduced in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Brannigan, Grace, LeBard, David N., Hénin, Jérôme, Eckenhoff, Roderic G., Klein, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922517/
https://ncbi.nlm.nih.gov/pubmed/20660787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008534107
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!