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General Anesthetics Predicted to Block the GLIC Pore with Micromolar Affinity
Although general anesthetics are known to modulate the activity of ligand-gated ion channels in the Cys-loop superfamily, there is at present neither consensus on the underlying mechanisms, nor predictive models of this modulation. Viable models need to offer quantitative assessment of the relative...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364936/ https://ncbi.nlm.nih.gov/pubmed/22693438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002532 |
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