A defined structural unit enables de novo design of small-molecule–binding proteins

by Polizzi, Nicholas F., DeGrado, William F.
Published in Science (2020)

Physical constraints on charge transport through bacterial nanowires

by Polizzi, Nicholas F., Skourtis, Spiros S., Beratan, David N.
Published 2012

Mean First-Passage Times in Biology

by Polizzi, Nicholas F., Therien, Michael J., Beratan, David N.
Published in Isr J Chem (2016)

Biochemistry and Theory of Proton-Coupled Electron Transfer

by Migliore, Agostino, Polizzi, Nicholas F., Therien, Michael J., Beratan, David N.
Published in Chem Rev (2014)

Defusing redox bombs?

by Polizzi, Nicholas F., Migliore, Agostino, Therien, Michael J., Beratan, David N.
Published in Proc Natl Acad Sci U S A (2015)

Engineering opposite electronic polarization of singlet and triplet states increases the yield of high-energy photoproducts

by Polizzi, Nicholas F., Jiang, Ting, Beratan, David N., Therien, Michael J.
Published in Proc Natl Acad Sci U S A (2019)

Where Is the Electronic Oscillator Strength? Mapping Oscillator Strength across Molecular Absorption Spectra

by Zheng, Lianjun, Polizzi, Nicholas F., Dave, Adarsh R., Migliore, Agostino, Beratan, David N.
Published in J Phys Chem A (2016)

Charge Transfer in Dynamical Biosystems, or The Treachery of (Static) Images

by Beratan, David N., Liu, Chaoren, Migliore, Agostino, Polizzi, Nicholas F., Skourtis, Spiros S., Zhang, Peng, Zhang, Yuqi
Published in Acc Chem Res (2014)

Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters

by Thomaston, Jessica L., Polizzi, Nicholas F., Konstantinidi, Athina, Wang, Jun, Kolocouris, Antonios, DeGrado, William F.
Published in J Am Chem Soc (2018)

Modulating Integrin αIIbβ3 Activity through Mutagenesis of Allosterically Regulated Intersubunit Contacts

by Tan, Sophia K., Fong, Karen P., Polizzi, Nicholas F., Sternisha, Alex, Slusky, Joanna S. G., Yoon, Kyungchul, DeGrado, William F., Bennett, Joel S.
Published in Biochemistry (2019)

Inhibitor binding mode and allosteric regulation of Na(+)-glucose symporters

by Bisignano, Paola, Ghezzi, Chiara, Jo, Hyunil, Polizzi, Nicholas F., Althoff, Thorsten, Kalyanaraman, Chakrapani, Friemann, Rosmarie, Jacobson, Matthew P., Wright, Ernest M., Grabe, Michael
Published in Nat Commun (2018)

Strategy for designing hyperstable, non-natural protein-ligand complexes with sub-Å accuracy

by Polizzi, Nicholas F., Wu, Yibing, Lemmin, Thomas, Maxwell, Alison M., Zhang, Shao-Qing, Rawson, Jeff, Beratan, David N., Therien, Michael J., DeGrado, William F.
Published in Nat Chem (2017)

Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein

by Polizzi, Nicholas F., Eibling, Matthew J., Perez-Aguilar, Jose Manuel, Rawson, Jeff, Lanci, Christopher J., Fry, H. Christopher, Beratan, David N., Saven, Jeffery G., Therien, Michael J.
Published in J Am Chem Soc (2016)

Allosteric cooperation in a de novo-designed two-domain protein

by Pirro, Fabio, Schmidt, Nathan, Lincoff, James, Widel, Zachary X., Polizzi, Nicholas F., Liu, Lijun, Therien, Michael J., Grabe, Michael, Chino, Marco, Lombardi, Angela, DeGrado, William F.
Published in Proc Natl Acad Sci U S A (2020)

Zinc-binding structure of a catalytic amyloid from solid-state NMR

by Lee, Myungwoon, Wang, Tuo, Makhlynets, Olga V., Wu, Yibing, Polizzi, Nicholas F., Wu, Haifan, Gosavi, Pallavi M., Stöhr, Jan, Korendovych, Ivan V., DeGrado, William F., Hong, Mei
Published in Proc Natl Acad Sci U S A (2017)

Excitation energy-dependent photocurrent switching in a single-molecule photodiode

by Shan, Bing, Nayak, Animesh, Williams, Olivia F., Yost, Dillon C., Polizzi, Nicholas F., Liu, Yanming, Zhou, Ninghao, Kanai, Yosuke, Moran, Andrew M., Therien, Michael J., Meyer, Thomas J.
Published in Proc Natl Acad Sci U S A (2019)

Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins

by Yang, Bing, Wang, Nanxi, Schnier, Paul D., Zheng, Feng, Zhu, He, Polizzi, Nicholas F., Ittuveetil, Avinash, Saikam, Varma, DeGrado, William F., Wang, Qian, Wang, Peng G., Wang, Lei
Published in J Am Chem Soc (2019)