PET Diagnostic Molecules Utilizing Multimeric Cyclic RGD Peptide Analogs for Imaging Integrin α(v)β(3) Receptors

Por Liolios, Christos, Sachpekidis, Christos, Kolocouris, Antonios, Dimitrakopoulou-Strauss, Antonia, Bouziotis, Penelope
Publicado no Molecules (2021)

Influence of an Additional Amino Group on the Potency of Aminoadamantanes Against Influenza Virus A. II – Synthesis of Spiropiperazines and In-Vitro Activity Against Influenza A H3...

Por Fytas, Christos, Kolocouris, Antonios, Fytas, George, Grigoris, Zoidis, Valmas, Charalambos, Basler, Christopher F.
Publicado em 2010

The L46P Mutant Confers a Novel Allosteric Mechanism of Resistance Toward the Influenza A Virus M2 S31N Proton Channel Blockers

Por Musharrafieh, Rami, Lagarias, Panagiotis I., Ma, Chunlong, Tan, Gene S., Kolocouris, Antonios, Wang, Jun
Publicado no Mol Pharmacol (2019)

Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters

Por Thomaston, Jessica L., Polizzi, Nicholas F., Konstantinidi, Athina, Wang, Jun, Kolocouris, Antonios, DeGrado, William F.
Publicado no J Am Chem Soc (2018)

Investigation of the Drug Resistance Mechanism of M2-S31N Channel Blockers through Biomolecular Simulations and Viral Passage Experiments

Por Musharrafieh, Rami, Lagarias, Panagiotis, Ma, Chunlong, Hau, Raymond, Romano, Alex, Lambrinidis, George, Kolocouris, Antonios, Wang, Jun
Publicado no ACS Pharmacol Transl Sci (2020)

Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in Phospholipid Bilayers

Por Mandala, Venkata S., McKay, Matthew J., Shcherbakov, Alexander A., Dregni, Aurelio J., Kolocouris, Antonios, Hong, Mei
Publicado no Res Sq (2020)

Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers

Por Mandala, Venkata S., McKay, Matthew J., Shcherbakov, Alexander A., Dregni, Aurelio J., Kolocouris, Antonios, Hong, Mei
Publicado no Nat Struct Mol Biol (2020)

Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors

Por Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Publicado no bioRxiv (2020)

Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors

Por Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Publicado no ACS Pharmacol Transl Sci (2020)

Affinity of Rimantadine Enantiomers against Influenza A/M2 Protein Revisited

Por Drakopoulos, Antonios, Tzitzoglaki, Christina, Ma, Chulong, Freudenberger, Kathrin, Hoffmann, Anja, Hu, Yanmei, Gauglitz, Günter, Schmidtke, Michaela, Wang, Jun, Kolocouris, Antonios
Publicado no ACS Med Chem Lett (2017)

X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance

Por Thomaston, Jessica L., Konstantinidi, Athina, Liu, Lijun, Lambrinidis, George, Tan, Jingquan, Caffrey, Martin, Wang, Jun, DeGrado, William F., Kolocouris, Antonios
Publicado no Biochemistry (2020)

Pharmacological characterisation of novel adenosine A(3) receptor antagonists

Por Barkan, Kerry, Lagarias, Panagiotis, Stampelou, Margarita, Stamatis, Dimitrios, Hoare, Sam, Safitri, Dewi, Klotz, Karl-Norbert, Vrontaki, Eleni, Kolocouris, Antonios, Ladds, Graham
Publicado no Sci Rep (2020)

Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A

Por Kolocouris, Antonios, Tzitzoglaki, Christina, Johnson, F. Brent, Zell, Roland, Wright, Anna K., Cross, Timothy A., Tietjen, Ian, Fedida, David, Busath, David D.
Publicado em 2014

Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants

Por Drakopoulos, Antonios, Tzitzoglaki, Christina, McGuire, Kelly, Hoffmann, Anja, Konstantinidi, Athina, Kolokouris, Dimitrios, Ma, Chunlong, Freudenberger, Kathrin, Hutterer, Johanna, Gauglitz, Günter, Wang, Jun, Schmidtke, Michaela, Busath, David D., Kolocouris, Antonios
Publicado no ACS Med Chem Lett (2018)

Chemical Probes for Blocking of Influenza A M2 WT and S31N Channels

Por Tzitzoglaki, Christina, McGuire, Kelly, Lagarias, Panagiotis, Konstantinidi, Athina, Hoffmann, Anja, Fokina, Natalie A., Ma, Chulong, Papanastasiou, Ioannis P., Schreiner, Peter R., Vázquez, Santiago, Schmidtke, Michaela, Wang, Jun, Busath, David D., Kolocouris, Antonios
Publicado no ACS Chem Biol (2020)

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M(pro) and cathepsin L

Por Sacco, Michael Dominic, Ma, Chunlong, Lagarias, Panagiotis, Gao, Ang, Townsend, Julia Alma, Meng, Xiangzhi, Dube, Peter, Zhang, Xiujun, Hu, Yanmei, Kitamura, Naoya, Hurst, Brett, Tarbet, Bart, Marty, Michael Thomas, Kolocouris, Antonios, Xiang, Yan, Chen, Yu, Wang, Jun
Publicado no bioRxiv (2020)

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M(pro) and cathepsin L

Por Sacco, Michael Dominic, Ma, Chunlong, Lagarias, Panagiotis, Gao, Ang, Townsend, Julia Alma, Meng, Xiangzhi, Dube, Peter, Zhang, Xiujun, Hu, Yanmei, Kitamura, Naoya, Hurst, Brett, Tarbet, Bart, Marty, Michael Thomas, Kolocouris, Antonios, Xiang, Yan, Chen, Yu, Wang, Jun
Publicado no Sci Adv (2020)

Membrane Protein Structure, Function and Dynamics: A Perspective from Experiments and Theory

Por Cournia, Zoe, Allen, Toby W., Andricioaei, Ioan, Antonny, Bruno, Baum, Daniel, Brannigan, Grace, Buchete, Nicolae-Viorel, Deckman, Jason T., Delemotte, Lucie, del Val, Coral, Friedman, Ran, Gkeka, Paraskevi, Hege, Hans-Christian, Hénin, Jérôme, Kasimova, Marina A., Kolocouris, Antonios, Klein, Michael L., Khalid, Syma, Lemieux, M. Joanne, Lindow, Norbert, Roy, Mahua, Selent, Jana, Tarek, Mounir, Tofoleanu, Florentina, Vanni, Stefano, Urban, Sinisa, Wales, David J., Smith, Jeremy C., Bondar, Ana-Nicoleta
Publicado no J Membr Biol (2015)