A carregar...
The L46P Mutant Confers a Novel Allosteric Mechanism of Resistance Toward the Influenza A Virus M2 S31N Proton Channel Blockers
The Food and Drug Administration–approved influenza A antiviral amantadine inhibits the wild-type (WT) AM2 channel but not the S31N mutant predominantly found in circulating strains. In this study, serial viral passages were applied to select resistance against a newly developed isoxazole-conjugated...
Na minha lista:
| Publicado no: | Mol Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608606/ https://ncbi.nlm.nih.gov/pubmed/31175183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.116640 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|