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Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers

The majority of human influenza A viruses currently in circulation carry the amantadine-resistant AM2-S31N channel mutation. We previously discovered a series of AM2-S31N inhibitors with potent antiviral activity against both oseltamivir-sensitive and -resistant influenza A viruses. To understand th...

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書目詳細資料
發表在:Antiviral Res
Main Authors: Musharrafieh, Rami, Ma, Chunlong, Wang, Jun
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891360/
https://ncbi.nlm.nih.gov/pubmed/29518414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.03.002
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