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Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers
The majority of human influenza A viruses currently in circulation carry the amantadine-resistant AM2-S31N channel mutation. We previously discovered a series of AM2-S31N inhibitors with potent antiviral activity against both oseltamivir-sensitive and -resistant influenza A viruses. To understand th...
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| Veröffentlicht in: | Antiviral Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5891360/ https://ncbi.nlm.nih.gov/pubmed/29518414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.03.002 |
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