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Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins

Expansion of the genetic code with unnatural amino acids (Uaas) has significantly increased the chemical space available to proteins for exploitation. Due to the inherent limitation of translational machinery and the required compatibility with biological settings, function groups introduced via Uaa...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Yang, Bing, Wang, Nanxi, Schnier, Paul D., Zheng, Feng, Zhu, He, Polizzi, Nicholas F., Ittuveetil, Avinash, Saikam, Varma, DeGrado, William F., Wang, Qian, Wang, Peng G., Wang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556376/
https://ncbi.nlm.nih.gov/pubmed/31038942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02611
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