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Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates
Nonenzymatic post-translational modification (PTM) of proteins is a fundamental molecular process of aging. The combination of various modifications and their accumulation with age not only affects function, but leads to crosslinking and protein aggregation. In this study, aged human lens proteins w...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114717/ https://ncbi.nlm.nih.gov/pubmed/24134651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12164 |
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