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Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates
Nonenzymatic post-translational modification (PTM) of proteins is a fundamental molecular process of aging. The combination of various modifications and their accumulation with age not only affects function, but leads to crosslinking and protein aggregation. In this study, aged human lens proteins w...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BlackWell Publishing Ltd
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114717/ https://ncbi.nlm.nih.gov/pubmed/24134651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12164 |
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